Patent for Sale:

Metered Dose Inhaler (MDI) Spacer    

Spacer for delivery of medications from an inhaler to children and breathing impaired patients


Metered Dose Inhalers (MDIs) dispense aerosolized drugs that are inhaled by patients. An inhaler spacer reduces aerosol droplet size by evaporation for deep lung penetration. This also reduces the number of larger droplets that deposit in the upper airways, get swallowed, and contribute to side effects.

Compared to available MDI inhaler spacers, this unique spacer provides:

- Less drug loss on spacer walls,
- More drug deep into lungs
- Easier inhalation

Primary Application of the Technology

Drug delivery to lung, inhalation therapy for asthma and other pulmonary diseases.

How the Technology Solves the Problem

This spacer technology has been designed and optimized through computer simulations (computational fluid dynamics).

The conical shape of this spacer is combined with air slits to generate an air cushion that keeps drug aerosols off of the spacer walls. Mixing outside air with the dispensed spray inside the spacer slows the flow of drug, allowing more time for evaporation and reducing the size of droplets. Introducing outside air also makes inhalation easier for breathing impaired patients by reducing resistance.

A unique one-way valve, modeled after the tricuspid valve in the heart, opens more easily than other valves during inhalation and closes completely during exhalation. This helps breathing impaired patients to get more dispensed drug deep into the lungs and to hold the drug there longer before exhaling.

Competitive Advantage

Prototype testing has indicated that this inhaler spacer delivers up to 15% more drug with up to 30% higher efficiency than the market leader.

Patent Summary

U.S. Patent Classes & Classifications Covered in this listing:

Class 128: Surgery

Methods of treatment of the living body and apparatus used in the inspection and treatment of diseases, wounds, and other abnormal conditions of the bodies of humans and lower animals. This class includes methods and means for manufacturing surgical appliances which are not classifiable in other classes.

Subclass 200.22: Gas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.)
Subclass 200.23: Pre-pressurized container holding medicament
Subclass 203.15: Particulate treating agent carried by breathed gas