Patent for Sale:

Agglutination Immunoassay Based on Nucleic-Acid Bound Polypeptide    

Immunoassay Which Overcomes Limitations of Existing Immunoassays Through Use of a Nucleic-Acid Bound Polypeptide

Overview

A nucleic acid bonded polypeptide to which various characteristics of the polypeptide are changed by this invention without changing the antigenicity of polypeptide is provided. This invention allows collection of the gene products which were conventionally collected in the insoluble fraction through a gene engineering technique in a soluble fraction.

Primary Application of the Technology

Medical diagnostics

The Problem Solved by the Technology

By combining a nucleic acid with a polypeptide, the character of the polypeptide can be changed without changing the antigenicity of the polypeptide. Thus, an immunoassay may become possible where the nucleic acid - bonded polypeptide is an antigen.

Comments on Deal Structure, Potential Terms and Restrictions

Sale of the patent to an operating company, not a non-practicing entity.

The seller would like to be granted a license back.

Patent Summary

U.S. Patent Classes & Classifications Covered in this listing:

Class 436: Chemistry: Analytical And Immunological Testing

This is the generic class for: chemical test standards, analytical compositions, and processes which involve a chemical reaction for determining qualitatively or quantitatively the presence of a chemical element, compound or complex in a composition or a chemical compound, or an element or radical in a compound; processes for analysis which involve an in vitro antigen-antibody, immunological or protein binding interaction other than those involving a living antigen, or enzyme label; and processes of analysis or study of the chemical properties of a sample; the physiological effect of a sample; or chemical determination of a physical property of a sample. Compositions and their mere methods of use of thermoparticulating compositions. Combinations of tests or measurements with methods of regulating a chemical reaction not otherwise provided for in a chemical synthesis class or otherwise.

Subclass 501: BIOSPECIFIC LIGAND BINDING ASSAY
Subclass 518: INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS
Subclass 523: Carrier is particulate and the particles are of intentionally different sizes or impregnated differently with the immunochemicals
Subclass 533: Carrier is water suspendible particles (e.g., latex, etc.)
Subclass 534: Carrier is water suspendible particles
Subclass 807: APPARATUS INCLUDED IN PROCESS CLAIM (E.G., PHYSICAL SUPPORT STRUCTURES, ETC.)
Subclass 824: IMMUNOLOGICAL SEPARATION TECHNIQUES

Class 422: Chemical Apparatus And Process Disinfecting, Deodorizing, Preserving, Or Sterilizing

This is a generic class for (1) processes of disinfecting, deodorizing, preserving or sterilizing and (2) apparatus for (a) carrying out chemical reactions, (b) preparing or treating chemical compounds or compositions even though only a physical reaction is discernible, (c) performing an analysis which involves either a chemical reaction or a physical reaction not elsewhere provided, for and (d) carrying out the above processes not elsewhere provided for.

Subclass 72: Including centrifuge

Class 435: Chemistry: Molecular Biology And Microbiology

This class provides for the following subject matter when not provided for elsewhere: A process of using a microorganism or enzyme to synthesize a chemical product. A process of treating a material with a microorganism or enzyme to separate, liberate, or purify a preexisting substance. An in vitro process of measuring and testing in which: (1) A microorganism or enzyme is used to determine the presence or identity of a compound or composition in a sample; (2) A microorganism is identified by propagation; (3) An enzyme is identified by its catalytic activity; (4) The presence of microorganisms is detected; (5) A live microorganism is used in an antigen antibody test as an antigen; (6) Fixed or stabilized nonliving microorganisms, cells, or tissues are involved. A process of propagating a microorganism. A process in which the genetic structure of a microorganism or extrachromosomal genetic structure is altered. A process of organ or tissue maintenance. A process of mashing or malting. Microorganisms, per se, or the subcellular parts thereof. Enzymes, immobilized enzymes or enzyme containing compositions not otherwise provided for and the processes for purifying enzymes or forming immobilized enzymes. Compositions claimed or solely disclosed as for the propagation of microorganisms or for measuring and testing processes. Using microorganisms to destroy hazardous or toxic waste.

Subclass 6: Involving nucleic acid
Subclass 7.1: Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay
Subclass 69.3: Antigens
Subclass 69.7: Fusion proteins or polypeptides
Subclass 174: CARRIER-BOUND OR IMMOBILIZED ENZYME OR MICROBIAL CELL; CARRIER-BOUND OR IMMOBILIZED CELL; PREPARATION THEREOF
Subclass 402: Support is a coated or treated surface
Subclass 403: Support is a suspendable particle