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Patent for License:

Gene DNA Encoding of a Protein    

Used in the preparation of cells for gene therapy and in the prevention and treatment of Alzheimers.

Overview

A gene encoding protein with high-affinity choline transporter activity. Until now the molecular properties of a protein with a high-affinity choline transporter have been unknown. The gene encolding provides a physiologically important protein.

Primary Application of the Technology

Alzheimers disease; gene therapy

Comments on Deal Structure, Potential Terms and Restrictions

Patent available for commercialization, enforcement rights negotiable.

Patent Summary

U.S. Patent Classes & Classifications Covered in this Patent:

Class 536: Organic Compounds -- Part Of The Class 532 Series

The classes of the 532 series embrace monomeric organic carbon compounds and polymeric organic carbon compounds that are not solid synthetic resins, natural rubbers, or hydrocarbons.

Subclass 23.5: Encodes an animal polypeptide

Class 435: Chemistry: Molecular Biology And Microbiology

This class provides for the following subject matter when not provided for elsewhere: A process of using a microorganism or enzyme to synthesize a chemical product. A process of treating a material with a microorganism or enzyme to separate, liberate, or purify a preexisting substance. An in vitro process of measuring and testing in which: (1) A microorganism or enzyme is used to determine the presence or identity of a compound or composition in a sample; (2) A microorganism is identified by propagation; (3) An enzyme is identified by its catalytic activity; (4) The presence of microorganisms is detected; (5) A live microorganism is used in an antigen antibody test as an antigen; (6) Fixed or stabilized nonliving microorganisms, cells, or tissues are involved. A process of propagating a microorganism. A process in which the genetic structure of a microorganism or extrachromosomal genetic structure is altered. A process of organ or tissue maintenance. A process of mashing or malting. Microorganisms, per se, or the subcellular parts thereof. Enzymes, immobilized enzymes or enzyme containing compositions not otherwise provided for and the processes for purifying enzymes or forming immobilized enzymes. Compositions claimed or solely disclosed as for the propagation of microorganisms or for measuring and testing processes. Using microorganisms to destroy hazardous or toxic waste.

Subclass 252.3: Transformants (e.g., recombinant DNA or vector or foreign or exogenous gene containing, fused bacteria, etc.)
Subclass 6: Involving nucleic acid
Subclass 7.2: Involving a micro-organism or cell membrane bound antigen or cell membrane bound receptor or cell membrane bound antibody or microbial lysate
Subclass 7.21: Animal cell
Subclass 69.1: Recombinant DNA technique included in method of making a protein or polypeptide
Subclass 325: ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE
Subclass 353: Rat (i.e., Rattus)
Subclass 320.1: VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)

Class 436: Chemistry: Analytical And Immunological Testing

This is the generic class for: chemical test standards, analytical compositions, and processes which involve a chemical reaction for determining qualitatively or quantitatively the presence of a chemical element, compound or complex in a composition or a chemical compound, or an element or radical in a compound; processes for analysis which involve an in vitro antigen-antibody, immunological or protein binding interaction other than those involving a living antigen, or enzyme label; and processes of analysis or study of the chemical properties of a sample; the physiological effect of a sample; or chemical determination of a physical property of a sample. Compositions and their mere methods of use of thermoparticulating compositions. Combinations of tests or measurements with methods of regulating a chemical reaction not otherwise provided for in a chemical synthesis class or otherwise.

Subclass 501: BIOSPECIFIC LIGAND BINDING ASSAY

Class 530: Chemistry: Natural Resins Or Derivatives; Peptides Or Proteins; Lignins Or Reaction Products Thereof

Subclass 350: PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES
Subclass 388.22: Binds receptor (e.g., transferrin receptor, Fc receptor, dihydropyridine receptor, IL-2 receptor, etc.)

Class 800: Multicellular Living Organisms And Unmodified Parts Thereof And Related Processes

This is the class for living multicellular organisms (nonhuman animals and plants) and separated or severed parts thereof that have not undergone any modification or treatment subsequent to their separation. These organisms or parts thereof may be genetically modified. This class also includes processes of producing said multicellular organisms and of using said organisms (nonhuman animals) in testing and protein production processes. This class provides for the following products: living multicellular organisms, living products, separated or severed parts of multicellular plants and transgenic nonhuman animals which have not been modified or treated subsequent to their separation. This class provides for the following processes: methods of plant breeding; methods of mutating plants; methods of producing plants using somatic cell fusion; and methods of introducing nucleic acid into or rearrangement of genetic material within a plant. All of these methods result in a living plant or plant part.

Subclass 14: Mammal
Subclass 18: Mouse

European Patent Classes & Classifications Covered in this Patent:

Class G01N33: Physics - Measuring

Investigating or analysing materials by determining their chemical or physical properties. Investigating or analysing materials by specific methods not covered by the preceding groups.

Class C07K14: Chemistry; Metallurgy - Organic Chemistry

Peptides. Peptides having more than 20 amino acids; gastrins; somatostatins; melanotropins; derivatives thereof.