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Diagnostics - Breaking Stories from 3rd-Party News
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 News Clips—Breaking
Stories from 3rd-Party Newswires |
Shire Paying Jerini $519M for HAE Compound Firazyr
[treatment] [diagnosed] [drug] [financial] [disease]
LONDON - Shire Ltd. is buying Jerini AG in a cash deal valuing the German company at €328 million (US$519 million) to acquire Firazyr, (Icatibant) a treatment for hereditary angioedema (HAE), which is due to be launched in Europe by the end of the year. ... Russell said Shire will dispose of Jerini's other assets, including Jerini Ophthalmic Inc., a U.S. subsidiary developing treatments for wet age-related macular degeneration, and JPT Peptide Technologies GmbH, a peptide manufacturing facility....
Relevance: 22
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Clearstate Introduces Assay Insights - First In-depth and Comprehensive IVD Assay Dataset Showing Volume Consumption by
[diagnostics] [medical] [Molecular] [infectious]
Singapore (PRWEB) July 5, 2008 -- Clearstate, a premier research consulting firm offering intelligence and specialized marketing information services in medical diagnostics, announced today the introduction of the Gateway's Assay Insights, the first in-depth in-vitro diagnostics (IVD) assay database to report volume and value demand of Clinical Diagnostics assays by type of test and brand in major Asian markets. ...
Relevance: 70
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Dramatic Increase in 'Tommy John' Surgery in Young Patients Cause for Concern
[diagnostic] [treatment] [prevention]
?The increase in the number of UCL reconstructions being done now can be attributed to many things: improved diagnostic techniques, heightened awareness, increased chance of positive outcome with current surgical techniques, but most importantly, the overuse of young throwing arms,? said Dr. ... Upside to ?Epidemic? Surgery: 83% Successful in Return to Play, New Research Finds...
Relevance: 5
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Glaucoma Treatment Can Prevent Blindness
[Prevent] [disease] [detected] [Treatment] [Medical]
Glaucoma Treatment Can Prevent Blindness ... In one report, researchers say they found traditional surgery for glaucoma has better outcomes than using glaucoma drainage devices. ...
Relevance: 59
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Playing It Safe With High School Sports
[prevention] [preventing] [Disease] [detect] [treatment]
Coaches, athletic trainers focus on prevention, better treatment for young athletes ... But new research suggests that high school football coaches are getting a lot better at spotting a concussion and managing the problem, although there's still room for improvement....
Relevance: 33
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Commentary: Improving breast cancer treatment
[cancer] [detection] [prevention] [disease] [preventive]
The conference's directive is to push researchers to think "out of the box" for potential treatments, methods of detection and prevention in new ways. ... Billions of dollars have been dedicated to breast cancer research in the last decade. ...
Relevance: 64
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Defining the blueprint of the cancer genome
[genome] [diagnostic] [cancer] [cell] [cellular]
These mutational analyses provide a window into the genetic landscape of human cancer, indicate new targets for personalized diagnostic and therapeutic intervention, and suggest lessons for future large-scale genomic analyses in human tumors. ... To date, however, only a small fraction of genes has been analyzed and the number and type of alterations responsible for the development of common tumor types are unknown. ...
Relevance: 59
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Peculiar Morphology of Stones in Primary Hyperoxaluria
[diagnosis] [diagnostic tool] [disease]
However, although nephrolithiasis is the revealing symptom in the great majority of patients with this disease at any age, until now little attention has been paid to the analysis of stones as a possible diagnostic tool....
Relevance: 13
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A Population Study of Endomyocardial Fibrosis in a Rural Area of Mozambique
[disease] [diagnostic] [treatment] [echocardiography] [prognosis]
It has no specific treatment and carries a poor prognosis, since most patients present with advanced heart failure. ... Major and minor diagnostic criteria were defined, and a severity score was developed and applied. ...
Relevance: 78
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Noninvasive Monitoring of Tumors
[drugs] [cell] [treatment] [disease] [cancer]
Nonetheless, such advances have been limited, and the prognosis for patients with advanced disease remains grim. ... The treatment of non-small-cell lung cancer has made limited but clinically significant progress during the past two decades of clinical research. ...
Relevance: 69
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Detection of Mutations in EGFR in Circulating Lung-Cancer Cells
[Detection] [Cells] [detectable] [Molecular] [detect] [non small cell]
Detection of Mutations in EGFR in Circulating Lung-Cancer Cells ... Panel A shows serial analyses of the numbers of circulating tumor cells (CTCs) per milliliter (red curve) and the radiographic tumor burden in centimeters (blue curve) in four patients with non-small-cell lung cancer with EGFR mutations, as measured at multiple time points during the course of treatment with gefitinib, another chemotherapy agent (chemo), or an experimental agent (exp). ...
Relevance: 84
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Functional Genomics Identifies ABCC3 as a Mediator of Taxane Resistance in HER2-Amplified Breast Cancer
[cell] [Genomics] [Diagnostics] [Cancer] [Molecular]
Departments of 1 Oncology Diagnostics, 2 Bioinformatics, and 3 Molecular Biology, Genentech, Inc., South San Francisco, California ... We also show that amplification of ABCC3 is present in primary breast tumors and that it occurs predominantly in HER2-amplified and luminal tumors, and we report on development of a specific fluorescence in situ hybridization assay that may have utility as a predictive biomarker of taxane resistance in breast cancer. ...
Relevance: 53
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Improving Diagnosis Of Osteoporosis: Computer Simulations Help Predict Fracture Risk
[early detection] [detection] [diagnosed] [disease] [prevent] [detect]
Scientists in future aim to advance simulation techniques to go beyond the calculation of static bone strength to the simulation of the actual formation of the fractures for individual patients, in yet another step towards the fast, reliable and early detection of people at high fracture risk. ... Improving Diagnosis Of Osteoporosis: Computer Simulations Help Predict Fracture Risk...
Relevance: 80
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In Vitro Fertilization: New Method Predicts Which Women WIll Get Pregnant
[treatment] [diagnoses] [drugs] [Technology]
— Researchers at the Stanford University School of Medicine have identified a method that can predict with 70 percent accuracy whether a woman undergoing in vitro fertilization treatment will become pregnant. ... ScienceDaily (July 4, 2008)...
Relevance: 48
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Prognostic Effect of Basal-Like Breast Cancers Is Time Dependent: Evidence from Tissue Microarray Studies on a
[prognostic] [diagnosis] [molecular] [Microbiology] [cancer]
Although complete concordance between methodologies was not observed for estrogen receptor and progesterone receptor, their associations with disease-free survival were consistent with established prognostic findings. ... Michael's Hospital; 2 Laboratory Medicine and Pathobiology, 3 Public Health Sciences, and 4 Department of Medical Genetics and Microbiology, University of Toronto; and 5 Samuel Lunenfeld Research Institute and 6 Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada...
Relevance: 45
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Myasthenia Gravis
[treatment] [cells] [diagnosed] [blood] [Medical]
However, women tend to be diagnosed before 40, while men are generally diagnosed after 60. ... Doctors at the University of California, San Diego Medical Center have recently performed an experimental treatment for a patient with severe MG symptoms, called a hematopoietic stem cell transplant. ...
Relevance: 55
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