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When HBV virus DNA is extracted from patients in early stage of infection or with low virus load（less than 10e2 copies/ml）,if there is no appropriate DNA concentration procedure and the HBV DNA can usually not be detected by quantitive PCR method. So it is necessary to develop a rapid and effective method to purify and concentrate the DNA of the HBV virus from a patients serum. We are looking for technologies that can deliver ten times DNA concentration of the HBV virus, from serum. IE. the detection sensibility of the diagnostic kit should be ≥10e2/ml. |
